Close-up of a green barley ear in a field
25 year anniversary

Recombinant growth factors & cytokines

Consistent growth factors ready to scale

Animal-free, plant-made growth factors and cytokines for human cell cultures, skincare, and cellular agriculture. Consistent quality, reliable supply, significant cost reduction.

ISO 9001 certified, supplying companies worldwide

Gloved hands holding a petri dish of green plant shoots on a lab bench

The supply problem

Growth factors shouldn't be the bottleneck

Inconsistent batches stall your work.

Variability in purity and bioactivity forces re-validation and risks your results.

Animal-derived inputs add biorisk.

Serum and animal-component inputs raise contamination and supply-chain risk.

Cost and scale don't add up.

Conventional growth factors are expensive and hard to scale from research to production.

Find your growth factors and cytokines

Start with your application

ORF Genetics produces and sells recombinant growth factors and cytokines. Pick your application to see the factors most teams use, then explore the full range. Quote-based ordering, no account needed.

Stem cell & regenerative research

ISOkine® human and mouse recombinant growth factors and cytokines for stem cell expansion, differentiation, organoid development, and regenerative medicine research. Animal-free, endotoxin-free.

  • EGF
  • FGF-2
  • GDNF
  • LIF
  • Noggin
  • NRG-1
  • SCF
  • … and more
Explore research
Three ORF Genetics EGF vials, 100 µg, with green caps

Cell & gene therapy

ISOkine® growth factors and cytokines for T-cell expansion, CAR-T workflows, and cell-therapy manufacturing. High-purity, animal-free, consistent batch-to-batch, and produced under ISO 9001.

  • Flt3-ligand
  • IL-7
  • IL-15
  • IL-18
  • IL-21
  • SCF
  • ... and more
Talk to a scientist
Three ORF Genetics EGF vials, 100 µg, with green caps

Organoids

ISOkine® growth factors for intestinal, lung, brain, and other organoid models. Consistent batch-to-batch performance for reproducible organoid formation.

  • EGF
  • FGF-2
  • FGF-10
  • KGF (FGF-7)
  • IGF-1
  • Noggin
  • PDGF-BB
  • ... and more
Talk to a scientist
Three ORF Genetics EGF vials, 100 µg, with green caps

Cultivated meat & seafood

MESOkine® species-specific growth factors for bovine, porcine, and avian cell culture, since 2019. Consistent purity and bioactivity from research to production scale. Tested and trusted by numerous companies globally.

  • EGF (porcine)
  • FGF-2 (bovine, porcine, avian)
  • IGF-1 LR3 (bovine, porcine)
  • LIF (bovine)
  • PDGF-BB (porcine)
  • Transferrin (bovine)
  • VEGF (bovine)
  • ... and more
Explore cultivated meat
MESOkine growth factor vial with green cap

Cosmetic ingredients

DERMOkine® plant-based signalling peptides for skin and hair formulations, since 2008. Animal-free, produced in barley seed, by-passing bacterial production. Suitable for cosmetic and dermatology applications.

  • Skin barrier and repair signals
  • Hair follicle growth factors
  • Animal-free, suitable for vegan formulations
  • Endotoxin-free
  • Economical production at scale
  • Provided with barley seed proteins
Talk to us
DERMOkine glass vial with a green cap, labelled orfgenetics.com

Why ORF

Consistent, plant-made, animal-free, cost-effective

Consistent quality & supply

Excellent performance in various applications. Every product is endotoxin-free with batch-to-batch reproducibility. Validate once, and scale with confidence, knowing every lot meets the same specification.

Significantly lower cost

Molecular farming economics let you scale from research to production without runaway reagent budgets. Cost-effective at every stage, from first experiment to commercial volume.

Biorisk-free, animal-free

Plant-produced and endotoxin-free by design. No animal-derived inputs means lower contamination risk and a simpler and safer supply chain, from bench to process development.

25 years of experience

Molecular farming since 2001, ISO 9001 certified, and on the road to GMP grade. A supplier with the track record and quality systems you can trust from development through scale-up.

By the numbers

A supply you can build a process on

Producing plant-based recombinant growth factors and cytokines since 2007. Research teams and companies worldwide standardise on ORF Genetics for purity, consistency, and reliable scale.

25 years

Pioneering molecular farming

ISO 9001

Road towards GMP grade in 2027

3

Product lines: biomedical research, cultivated meat, cosmetics

~150

Companies worldwide (as of 2026)

How we make them

Grown in barley, purified for the bench

Labelled flasks of barley seeds, dehulled seeds, milled seeds and purified proteins beside a small vial

Molecular farming in barley

Using both in-field and greenhouse cultivation. ORF's pioneering barley-seed expression platform produces recombinant proteins at scale. Providing a clean, animal-free production route, free from bacterial contaminants, serum and mammalian cell-culture inputs.

Barley seedlings growing in capped test tubes in a wire lab rack

Bio-risk free by design

A plant host carries no animal-derived contaminants. Every batch is endotoxin-free by design, reducing bio-risk for sensitive cell culture or dermatology application where purity directly affects outcomes.

Barley ear in a greenhouse lit by grow lights

Powered by geothermal energy

ORF's greenhouse operations run on Iceland's geothermal grid, giving each batch a low carbon footprint and contributing to a more sustainable, resilient supply chain.

Green barley ears growing in a field

Get started

Scale your process with a supply you can trust

Talk to our scientists about your application, or request a quote. Worldwide distribution, ISO 9001 certified.

Quote-based, no account needed. Datasheets available on request.