ISOkine™ growth factors and cytokines are biorisk-free since they are produced in the endosperm of barley seeds. They are animal and serum-free, void of antibiotics, endotoxin-free, pyrogenic and pro-inflammatory-free, void of bacteria, viruses and prions and are eukaryotic folded and glycosylated. Their production is environmentally friendly and CO2 neutral, as renewable, geothermal energy is used in their production. Furthermore, the biological activity typically is comparable or better than of other growth factors and cytokines on the market.